single use bioreactors

Single Use Bioreactors

Sterile. Scalable. Smart. (500mL - 10L)

KBiotech Single-Use Bioreactors (SUBs) and Single-Use Fermentors (SUFs) (500 mL – 10 L) bring fast, sterile, plug-and-run bioprocessing to cell culture, microbial fermentation, vaccines, and cell & gene therapy.

With pre-assembled disposable vessels, E-beam sterilization, and Smart-BioFlex™ control, they integrate natively with BioBook Compact™ and Modular Controllers.

Why Choose KBiotech SUB & SUFs?

Twin SUB & SUFs

Rapid Plug-and-Run Setup

Pre-assembled, sterile, single-use vessels with mounted impellers and auto-recognition reduce setup time by up to 90%.

Sterile & GMP-Ready by Design

E-beam sterilized (32 kGy), double-bagged for cleanroom handling, and supplied with full IQ/OQ/PQ documentation.

Smart-BioFlex™ Automation

Real-time dashboards, predictive control, secure data storage, and full 21 CFR Part 11 compliance.

Technical Specifications

Working Volumes

500 mL – 10 L; single, twin, or parallel (up to 12)

Materials

Medical-grade polycarbonate & nylon

Temperature Control

Jacketed, +4 °C to +50 °C (±0.1 °C)

Agitation

Magnetic drive; marine, Rushton, or axial impellers

Sterilization

Standard pH & DO; optional biomass, pCO₂, viability, multi-gas

Sensor Suite

E-beam 32 kGy; gamma-safe; double-bagged

Vessels & Accessories

Extend your BioBook Compact with a wide range of configurable vessels and accessories designed to support different scales, organisms, and applications.

Autoclavable benchtop vessels 100 mL-20 L

Glass Single wall / Jacketed from 50 mL-20 L

Single use benchtop vessels from 100 mL-10 L

Stainless steel benchtop vessels from 1L-20 L

Air Lift & Photobioreactors Vessels from 100 mL-20 L

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Continuous Processing & Downstream Integration

Upstream–downstream continuity, on your benchtop.

  • ATF: Ultra-high cell densities with low-shear circulation.
  • TFF: Stable medium exchange for extended continuous runs.
  • Smart Harvest: Weight-based, automated fluid management for consistent yields.

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Frequently Asked Questions

Yes — each reactor has its own sensors, gas mixing, agitation, and feeding controls.

Absolutely — full support for OPC UA, MQTT, REST API, and scripting ensures seamless digital integration.

Yes — our platform works with glass, single-use, stainless steel, and photobioreactor vessels, all auto-recognized via RFID.

Yes — both are fully supported with integrated pumps and ATF/TFF modules for continuous and intensified bioprocessing.

Yes — monitor and control your process through a secure web interface with real-time dashboards and audit logs.