single use bioreactors

Single Use Bioreactors

Sterile. Scalable. Smart. (500mL - 10L)

KBiotech Single-Use Bioreactors (SUBs) and Single-Use Fermentors (SUFs) (500 mL – 10 L) bring fast, sterile, plug-and-run bioprocessing to cell culture, microbial fermentation, vaccines, and cell & gene therapy.

With pre-assembled disposable vessels, E-beam sterilization, and Smart-BioFlex™ control, they integrate natively with BioBook Compact™ and Modular Controllers.

Why Choose KBiotech SUB & SUFs?

Twin SUB & SUFs

Rapid Plug-and-Run Setup

Pre-assembled, sterile, single-use vessels with mounted impellers and auto-recognition reduce setup time by up to 90%.

Sterile & GMP-Ready by Design

E-beam sterilized (32 kGy), double-bagged for cleanroom handling, and supplied with full IQ/OQ/PQ documentation.

Smart-BioFlex™ Automation

Real-time dashboards, predictive control, secure data storage, and full 21 CFR Part 11 compliance.

Technical Specifications

Working Volumes

500 mL – 10 L; single, twin, or parallel (up to 12)

Materials

Medical-grade polycarbonate & nylon

Temperature Control

Jacketed, +4 °C to +50 °C (±0.1 °C)

Agitation

Magnetic drive; marine, Rushton, or axial impellers

Sterilization

Standard pH & DO; optional biomass, pCO₂, viability, multi-gas

Sensor Suite

E-beam 32 kGy; gamma-safe; double-bagged

Single-Use Vessels Benchtop Bioreactors (100 mL – 10 L)

Ready-to-use single-use bioreactors for microbial and cell culture processes. Scalable from 100 mL to 10 L, they offer fast setup, sterile operation, and reliable control-ideal for R&D, process development, and small-scale production.

Single Use Vessels 100ml - 10L

Single Use Vessels 100ml – 10L

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Inline Analytics & PAT Modules

Enhance process understanding with real-time monitoring and control directly integrated into your bioreactor.

  • KG-FERM: Off-gas analysis (O₂, CO₂, CH₄, H₂, CO)
  • KBIO-TBD: Optical and capacitance biomass monitoring
  • LIVE-CELL™: Inline cell viability and density measurement
  • Raman Spectroscopy: Molecular fingerprinting for metabolites and product profiling
  • Automated Sampling Ports: Sterile inline collection for offline QC Advanced PAT tools for data-driven optimization and consistent bioprocess performance.

Continuous Processing & Downstream Integration

Achieve upstream–downstream continuity on your benchtop with KBIOTECH’s continuous bioprocess solutions.

  • ATF: Ultra-high cell densities with low-shear circulation.
  • TFF: Stable medium exchange for extended continuous runs.
  • Smart Harvest: Automated, weight-based fluid control for consistent yields. Efficient, scalable, and fully integrated from culture to harvest.

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Frequently Asked Questions

Yes — each reactor has its own sensors, gas mixing, agitation, and feeding controls.

Absolutely — full support for OPC UA, MQTT, REST API, and scripting ensures seamless digital integration.

Yes — our platform works with glass, single-use, stainless steel, and photobioreactor vessels, all auto-recognized via RFID.

Yes — both are fully supported with integrated pumps and ATF/TFF modules for continuous and intensified bioprocessing.

Yes — monitor and control your process through a secure web interface with real-time dashboards and audit logs.