Lab SIP Bioreactors

Why Choose Lab SIP Bioreactors?

Transform your lab into a scalable, smart bioprocessing hub.

Seamless Scale-Up

Consistent geometry (3:1, 2:1, 1.5:1 H/D ratios) and unified control logic enable reproducible results from 1 L lab vessels to 50 L pilot-scale fermenters.

Automated SIP & CIP

Fully integrated steam-in-place and clean-in-place cycles, eliminating manual sterilization steps and reducing turnaround time.

Exclusive ALLIONE Option

Patent-pending technology that combines SIP and CIP into a single automated cycle, unique on the market.

Technical Specifications

Working Volumes

1 L – 50 L (benchtop to skid-mounted formats)

Material

316L stainless steel; optional glass-steel hybrid

Sterilization & Cleaning

Automated SIP (121–130 °C) + CIP; optional ALLIONE unified cycle

Temperature Control

4 °C – 150 °C (±0.1 °C)

Agitation

0–2000 rpm; Marine, Rushton, or Axial impellers

Download Data Sheet

Benchtop SIP vs Skid-Mounted SIP Systems

Benchtop SIP

Best for: Labs, training, process development

Volume Range: 1L – 20 L
Format: Compact, plug-and-play
Allinone Option: Available
Installation: Rapid setup

Skid-Mounted SIP

Best for: Pilot, GMP-oriented workflows

Volume Range: 10 L – 50 L
Format: Industrial floor-mounted
Allione Option: Patent pending
Installation: Utilities integration

BioBook Modular Control Platform

One controller. Multiple scales. Total flexibility

Unified interface

from benchtop to pilot-scale SIP/CIP systems

Modular expansion

for pumps, sensors, gas mixing, analytics

Consistent logic & recipes

across all volumes

Industrial connectivity

via OPC-UA, Modbus, REST AP

Remote access

from desktop, tablet, or mobile

Learn More About BioBook Modular

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Inline Analytics & PAT Modules

KG-FERM — real-time off-gas (O₂, CO₂, CH₄, H₂, CO) analysis
KBIO-TBD — optical & capacitance biomass monitoring
LIVE-CELL™ — inline cell viability and density measurement
Inline Raman Spectroscopy — molecular fingerprinting for metabolite and product profiling
Automated Sampling Ports — sterile inline collection for offline QC

Continuous Processing & Downstream Integration

Upstream–downstream continuity, on your benchtop.

ATF: Ultra-high cell densities with low-shear circulation.
TFF: Stable medium exchange for extended continuous runs.
Smart Harvest: Weight-based, automated fluid management for consistent yields.

Downloads:

SmartBioFlex™ Software

Tecnnical Data Sheet