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CIP SIP Skid all in one bioreactors

CIP & SIP Skids

Automated, Compact Sterilization & Cleaning Unit for Vessels (1-5,000L)

The ALL-IN-ONE SIP & CIP System by KBiotech is a compact skid integrating both Steam-in-Place (SIP) and Clean-in-Place (CIP) functionalities into a single, mobile or fixed unit.

Engineered for biotech, pharmaceutical, nutraceutical, and industrial bioprocessing, it provides automated and validated sterilization and cleaning for bioreactors, fermenters, and process tanks ranging from 1 L to 5,000 L. Its compact footprint, modular design, and intelligent automation make it an ideal solution for facilities seeking reliability, compliance, and operational efficiency.

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Why Choose CIP & SIP Skids?

Dual-function design: Integrated SIP and CIP in a single compact, programmable skid.

Efficiency and sustainability: Up to 20% energy savings versus traditional sterilization systems, with optimized WFI water recirculation.

Automation & compliance: BIOFLEX™ SCADA + Siemens/Rockwell PLC, GMP-ready with PED 2014/68/EU and ASME VIII Div. 1 certifications.

Technical Specifications

Vessel Compatibility

1 L–5,000 L tanks (bioreactors, fermenters, process vessels).

Operating Range

Max 160 °C, up to 10 barg pressure.

Heating & Steam Output

5–100 kW power; 0–100 kg/h steam (customizable).

Construction

AISI 316L tanks, AISI 304 skid, Ra < 0.6 µm (electropolished).

Certifications

PED 2014/68/EU, ASME VIII Div. 1, ISO 9001

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Automation / Skid Design

Configurations

Skid-mounted, mobile (cleanroom-compatible wheels), or fixed base.

Multi-Vessel Operation

Optional manifold system for parallel tank routing.

Connections

Tri-clamp utility ports for quick installation and removal.

CIP Pumps

2.2 – 10 kW, fully customizable for flow and pressure.

Compact layout

Optimized for limited utility rooms and easy maintenance.

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

bioflex

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Accessories & Module Options

  • Probes: pH, conductivity, temperature 
  • Sensors: Steam & water pressure, level, and flow 
  • Safety: Overpressure valves, vacuum breakers, electrovalves 
  • Utilities: Chillers, manifolds, and recirculation modules

  • Custom configurations for multi-tank integration and utility optimization
Downloads:
SmartBioFlex™ Software
Tecnnical Data Sheet

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Call us or request a back call to contact our specialists

+41 916 300 115

For presales questions and your order status email us at

sales@kbiotech.ch
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Application Type
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Working Volume Range
Volumes range: 1L - 50L
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Sterilization in Place (SIP)
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Cleaning in Place (CIP)
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Automation Level
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Steam Generator Required
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Technical Specifications
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Frequently Asked Questions

Pharma, biotech, nutraceutical, industrial fermentation, and foodtech.

Compatible with vessels from 1 L to 5,000 L (custom scaling available).

Yes — available with cleanroom-grade lockable wheels.

Yes — compliant with PED, ASME VIII Div. 1, and ISO 9001.

Through a 15.6″ touchscreen HMI and BIOFLEX™ SCADA remote access