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BioBook Twin Bioreactor

Scalable Bioprocessing Without Limits (50 mL–20 L)

Unlock unmatched flexibility and control with the BioBook Twin Bioreactor — the first truly Twin benchtop platform that grows with your process.

Start with a single unit, then seamlessly expand to parallel bioreactor arrays for high-throughput experimentation and advanced process development.
Whether you’re working in R&D, pilot, or production, BioBook adapts to your evolving needs.

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Why Choose the BioBook Twin Bioreactor?

Modular & Expandable

Configure what you need today (control, gas, pumps, thermal), then add modules anytime. Scale experiments, run parallel setups, or upgrade functionality without downtime.

Seamless Scalability

Move effortlessly from 50 mL R&D runs to 20 L pilot and production without changing workflows or hardware.

Universal Compatibility

Glass, stainless steel, single-use, air-lift, and LED photobioreactors — all plug-and-play.

Technical Specifications

Scalable Working Volumes: 50 mL–20 L (30 L optional) for smooth R&D-to-pilot transitions in glass, disposable and stainless steel.

Precision Process Control: Temperature 2–80 °C (±0.1 °C) pH 0–14 (±0.01) DO 0–300 % (±0.1 %)

Level/Foam, ORP, Conductivity and Pressure Real-time monitoring for biomass, capacitance, dissolved CO₂, off-gas (O₂/CO₂,CH4,H2), glucose, lactate & Raman analytics.

Fluid & Gas Management: Up to 8 peristaltic pumps + 8 MFCs with overlay and backpressure control.

Regulatory Ready: 21 CFR Part 11 compliance, with audit trails and support for autoclave, SIP/CIP, or single-use workflows.

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Modular Architecture

Tailored to Your Process

Every BioBook™ Module is designed for precision, flexibility, and seamless integration, so your bioreactor evolves with your needs.

Vessels

Extend your Bioreactors with a wide range of configurable vessels designed to support different scales, organisms, and applications.

Glass Vessels Benchtop Bioreactors (50 mL – 20 L)

Versatile single-wall or jacketed glass bioreactors for microbial and cell culture applications. Delivering precise temperature control, scalability and full sensor integration from 50mL to 20L. Ideal for R&D and process development.

Single-Use Vessels Benchtop Bioreactors (100 mL – 10 L)

Ready-to-use single-use bioreactors for microbial and cell culture processes. Scalable from 100 mL to 10 L, they offer fast setup, sterile operation, and reliable control-ideal for R&D, process development, and small-scale production.

Stainless Steel Benchtop Bioreactors (1 L – 20 L)

Durable stainless steel bioreactors for advanced microbial and cell culture applications. Scalable from 1 L to 20 L, they ensure precise control, clean-in-place operation, and long-term reliability for R&D, scale-up, and pilot production.

Air-Lift & Photobioreactors (100 mL – 20 L)

Innovative air-lift and photobioreactor systems for algae, photosynthetic microorganisms, and cell culture. Scalable from 100 mL to 20 L, they offer gentle mixing, efficient gas exchange, and optimal light distribution for research and production.

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Inline Analytics & PAT Modules

Enhance process understanding with real-time monitoring and control directly integrated into your bioreactor.

  • KG-FERM: Off-gas analysis (O₂, CO₂, CH₄, H₂, CO)
  • KBIO-TBD: Optical and capacitance biomass monitoring
  • LIVE-CELL™: Inline cell viability and density measurement
  • Raman Spectroscopy: Molecular fingerprinting for metabolites and product profiling
  • Automated Sampling Ports: Sterile inline collection for offline QC Advanced PAT tools for data-driven optimization and consistent bioprocess performance.

Continuous Processing & Downstream Integration

Achieve upstream–downstream continuity on your benchtop with KBIOTECH’s continuous bioprocess solutions.

  • ATF: Ultra-high cell densities with low-shear circulation.
  • TFF: Stable medium exchange for extended continuous runs.
  • Smart Harvest: Automated, weight-based fluid control for consistent yields. Efficient, scalable, and fully integrated from culture to harvest.
Downloads:
Brochure
SmartBioFlex™ Software
Tecnnical Data Sheet

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Call us or request a back call to contact our specialists

+41 916 300 115

For presales questions and your order status email us at

sales@kbiotech.ch
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Got questions?
Well, we’ve got answers

Yes — with audit trails, encrypted storage, e-signatures, and role-based access.

Up to 12 per control rack, with automatic vessel recognition.

Yes — BioBook supports smooth scale-up from R&D to production scale.

Yes — TLS encryption, mirrored SSDs, and optional SSO/MFA.

Absolutely — BioBook is optimized for CAR-T, viral vectors, and exosome production.