BioBook parallel bioreactors

BioBook Parallel Bioreactor

High-Throughput Benchtop Bioreactor System (50 mL–20 L)

The BioBook™ Parallel Bioreactor is a next-generation high-throughput bioprocessing platform for cell culture, microbial fermentation, strain screening, synthetic biology, and process development.

Designed for parallel experimentation, scale-down models, and intensified processes, it supports up to 12 independently controlled bioreactors in one compact system—delivering maximum flexibility, reproducibility, and GMP-ready compliance.

Why Choose the BioBook Parallel Bioreactor?

Run 12 Bioreactors in Parallel

Each vessel operates independently with dedicated sensors, gas mixing, agitation, and feeding control.

Seamless Scale-Up

Flexible working volume from 50 mL to 20 L, covering early R&D through pilot-scale bioprocessing.

Smart & Compliant

Powered by BioFlex™ control software with digital twin, predictive analytics, inline PAT integration, and full 21 CFR Part 11 compliance.

Technical Specifications

Scalable Working Volumes: 50 mL – 20 L; supports micro-scale, lab-scale, and pilot-scale applications.

Precision Control: Independent gas blending (O₂, CO₂, N₂, air), up to 8 MFCs per rack, and 8 precision peristaltic pumps per vessel for fed-batch, perfusion, or continuous operation.

Agitation & Temperature: Direct drive agitation (0–2000 rpm), jacketed glass or Peltier modules, ±0.1 °C stability across all reactors.

Connectivity & Compliance: Inline PAT (biomass, off-gas, OD/turbidity, dissolved CO₂, Raman/IR), OPC UA/MQTT/REST API, Python/MATLAB scripting, SCADA/MES ready, SIP/CIP and autoclavable vessel options, fully GMP-compliant.

Modular Architecture

Designed for High-Throughput Bioprocessing

Every BioBook™ Module is designed for precision, flexibility, and seamless integration, so your bioreactor evolves with your needs:

Master Control Module

Centralized, intuitive interface with full traceability and secure digital control.

MFC module bioook parallel

Gas Mixing Module

Independent, high-accuracy delivery of O₂, CO₂, N₂, and air for optimal culture conditions.

pumps module bioook parallel

Pumps Module

Up to 8 configurable peristaltic pumps for feeds, nutrient dosing, and dynamic flow strategies.

Thermo Regulation Module

Fast, stable heating and cooling to protect sensitive cell cultures.

Vessels

Extend your Bioreactors with a wide range of configurable vessels designed to support different scales, organisms, and applications.

Glass Vessels Benchtop Bioreactors (50 mL – 20 L)

Versatile single-wall or jacketed glass bioreactors for microbial and cell culture applications. Delivering precise temperature control, scalability and full sensor integration from 50mL to 20L. Ideal for R&D and process development.

Single-Use Vessels Benchtop Bioreactors (100 mL – 10 L)

Ready-to-use single-use bioreactors for microbial and cell culture processes. Scalable from 100 mL to 10 L, they offer fast setup, sterile operation, and reliable control-ideal for R&D, process development, and small-scale production.

Stainless Steel Benchtop Bioreactors (1 L – 20 L)

Durable stainless steel bioreactors for advanced microbial and cell culture applications. Scalable from 1 L to 20 L, they ensure precise control, clean-in-place operation, and long-term reliability for R&D, scale-up, and pilot production.

Air-Lift & Photobioreactors (100 mL – 20 L)

Innovative air-lift and photobioreactor systems for algae, photosynthetic microorganisms, and cell culture. Scalable from 100 mL to 20 L, they offer gentle mixing, efficient gas exchange, and optimal light distribution for research and production.

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Inline Analytics & PAT Modules

Enhance process understanding with real-time monitoring and control directly integrated into your bioreactor.

  • KG-FERM: Off-gas analysis (O₂, CO₂, CH₄, H₂, CO)
  • KBIO-TBD: Optical and capacitance biomass monitoring
  • LIVE-CELL™: Inline cell viability and density measurement
  • Raman Spectroscopy: Molecular fingerprinting for metabolites and product profiling
  • Automated Sampling Ports: Sterile inline collection for offline QC Advanced PAT tools for data-driven optimization and consistent bioprocess performance.

Continuous Processing & Downstream Integration

Achieve upstream–downstream continuity on your benchtop with KBIOTECH’s continuous bioprocess solutions.

  • ATF: Ultra-high cell densities with low-shear circulation.
  • TFF: Stable medium exchange for extended continuous runs.
  • Smart Harvest: Automated, weight-based fluid control for consistent yields. Efficient, scalable, and fully integrated from culture to harvest.

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Got questions?
Well, we’ve got answers

Yes — each reactor has its own sensors, gas mixing, agitation, and feeding controls.

Yes — the platform supports OPC UA, MQTT, REST API, and scripting for seamless integration.

Yes — glass, single-use, stainless steel, and photobioreactor vessels are auto-recognized via RFID.

Yes — both are fully enabled through integrated pumps and ATF/TFF filtration modules.

Yes — a secure web interface provides real-time access, audit logs, and remote process control.