benchtop brioeactors

BioBook Compact Bioreactor

Universal Benchtop Bioreactor System (50 mL–20 L)

Next-generation scalability and control, in one compact platform. BioBook Compact brings industrial-grade performance to the laboratory.

Designed for microbial, mammalian, phototrophic, and continuous bioprocesses, it combines scalability, advanced control, and modular flexibility—from 50 mL to 20 L—in a single benchtop system.

Why Choose the BioBook Compact Benchtop Bioreactor?

Transform your lab into a scalable, smart bioprocessing hub.

Compact & Modular

Fits inside 60 cm benches and Class II cabinets — maximize lab space without compromise.

Scalable Volumes (50 mL–20 L)

Seamlessly move from R&D to pilot scale without changing systems.

Integrated PAT & AI Control

Real-time analytics, smart optimization, and reproducible results.

Technical Specifications

Flexible Working Volumes

50 mL → 20 L in a single platform — ideal for R&D through pilot scale.

Environmental Control

Temp 2–80 °C (±0.1), pH 0–14 (±0.01), DO 0–300 % (±0.1), plus foam & level control.

Gas & Feed Integration

5+ MFC gas mixing (air, O₂, CO₂, N₂, overlay), 4+ peristaltic pumps, ATF/TFF perfusion support.

Inline Analytics

Real-time PAT tools (biomass, off-gas O₂/CO₂/CH₄/H₂, Raman, metabolites).

Regulatory Compliance

21 CFR Part 11, GMP-ready, fully audit-trailed data.

Vessels

Extend your Bioreactors with a wide range of configurable vessels designed to support different scales, organisms, and applications.

Glass Vessels Benchtop Bioreactors (50 mL – 20 L)

Versatile single-wall or jacketed glass bioreactors for microbial and cell culture applications. Delivering precise temperature control, scalability and full sensor integration from 50mL to 20L. Ideal for R&D and process development.

Single-Use Vessels Benchtop Bioreactors (100 mL – 10 L)

Ready-to-use single-use bioreactors for microbial and cell culture processes. Scalable from 100 mL to 10 L, they offer fast setup, sterile operation, and reliable control-ideal for R&D, process development, and small-scale production.

Stainless Steel Benchtop Bioreactors (1 L – 20 L)

Durable stainless steel bioreactors for advanced microbial and cell culture applications. Scalable from 1 L to 20 L, they ensure precise control, clean-in-place operation, and long-term reliability for R&D, scale-up, and pilot production.

Air-Lift & Photobioreactors (100 mL – 20 L)

Innovative air-lift and photobioreactor systems for algae, photosynthetic microorganisms, and cell culture. Scalable from 100 mL to 20 L, they offer gentle mixing, efficient gas exchange, and optimal light distribution for research and production.

SmartBioFlex™ Control

Elevate your BioBook Compact bioreactor with BioFlex™ Software — a powerful, intuitive platform that simplifies process control, ensures regulatory compliance, and delivers real-time insights for smarter bioprocessing.

Seamless Integration

SmartBioFlex™ combines an industrial distributed control core with an intuitive web interface.

From Recipe to Data Export

Users build multiphase recipes via draganddrop cascades, monitor critical parameters remotely and export encrypted data directly to LIMS.

Audit Trails and Onboarding

A complete audit trail supports regulatory inspections, while onboarding guidance assists less experienced operators.

Inline Analytics & PAT Modules

Enhance process understanding with real-time monitoring and control directly integrated into your bioreactor.

  • KG-FERM: Off-gas analysis (O₂, CO₂, CH₄, H₂, CO)
  • KBIO-TBD: Optical and capacitance biomass monitoring
  • LIVE-CELL™: Inline cell viability and density measurement
  • Raman Spectroscopy: Molecular fingerprinting for metabolites and product profiling
  • Automated Sampling Ports: Sterile inline collection for offline QC Advanced PAT tools for data-driven optimization and consistent bioprocess performance.

Continuous Processing & Downstream Integration

Achieve upstream–downstream continuity on your benchtop with KBIOTECH’s continuous bioprocess solutions.

  • ATF: Ultra-high cell densities with low-shear circulation.
  • TFF: Stable medium exchange for extended continuous runs.
  • Smart Harvest: Automated, weight-based fluid control for consistent yields. Efficient, scalable, and fully integrated from culture to harvest.

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Frequently Asked Questions

Yes — includes audit trail, role-based access, e-signatures, and encrypted storage.

Single-use: under 45 minutes. Glass: about 2 hours including sterilization.

Yes — standard ports and APIs support reuse and third-party integration.

Yes — TLS encryption, mirrored SSDs, and optional SSO/MFA.

Yes — recipes and control logic transfer directly, with kLa correlations.