Compact Bioreactors & Fermenters
Swiss Precision. Smart Control. Compact Scale-Up.
Built to Accelerate Biotech Innovation
KBiotech Compact Bioreactors are designed for forward-thinking labs in biotech, pharma, and food tech. These systems streamline R&D, reduce time-to-validation, and bridge the gap from lab bench to pilot scale—all within a clean, compact footprint.
Where traditional benchtop systems are fixed, bulky, or slow to adapt, KBiotech stands apart. Our Smart-BioFlex™ software, format flexibility, and GMP upgrade paths make this platform ideal for labs that prioritize precision, agility, and compliance.
Why Compact: Engineered for Intelligent Bioprocessing
KBiotech Compact Bioreactors are designed to make advanced bioprocessing accessible from day one—whether you’re in a university lab, a biotech startup, or a fast-moving industrial R&D team.
Unlike conventional systems that require steep learning curves or complex setups, Compact offers:
- Plug-and-play simplicity: Preconfigured, prevalidated, and ready to run.
- Smart-BioFlex™ Software: Intuitive yet powerful—predicts and prevents process deviations in real time while giving users full control and flexibility.
- Versatile applications: One system for microbial, mammalian, plant, and synthetic workflows.
- Scalable design: Start with 50 mL and grow to 30 L—no platform switch needed.
- GMP-ready pathways: Compliance options built in, not bolted on.
- Twin Reactor Setup: Optimize faster by running two experiments in parallel.
- AI-Driven Control: Predictive automation maintains optimal growth conditions—no constant manual tuning needed.
- Built-In I/O Slots: Ready for integration with ancillary analyzers and external analytics platforms.
- Online analytics and ancillary bioprocess sensors are pre-integrated into the controller and Smart-BioFlex™ software—offering real-time connectivity with minimal integration time, zero need for extra software patches, and no return-to-vendor requirement unlike conventional systems.
It’s intelligent where it matters most—ease of use, reproducibility, and adaptability—so you can spend less time configuring and more time advancing your science.
Designed to Meet Modern Bioprocess Demands
| Feature | KBiotech Compact | Conventional Benchtop Systems |
|---|---|---|
| Lab Space Optimization | Biosafety cabinet–friendly | Often large and stationary |
| Workflow Flexibility | Multiple formats supported out-of-the-box | Format-specific setups |
| Process Monitoring | AI-driven with predictive alerts | Reactive, PID-based control |
| Scalability | One platform: 50 mL to 30 L | Scale change often requires different hardware |
| Compliance-Readiness | GMP upgrade kits available | Requires custom upgrades or system changes |
| Remote Access & Data Control | Web-based dashboards and full SCADA software integration | Rare or partial network access |
| Support Availability | International service and proactive maintenance | Often region-limited |
Application-Ready for Academic Labs, Startups & Industry
- Microbial fermentation (E. coli, yeast, anaerobes)
- Mammalian and stem cell culture (gentle mixing)
- CRISPR and gene editing workflows
- Alternative protein and bioplastic development
- Enzyme optimization and synthetic biology
At-a-Glance Technical Overview
Available Vessel Options
| Glass Vessels (single-wall and jacketed): | 250 mL to 20 L |
| Single-Use Vessels: | 500 mL, 1 L, 3 L, 5 L, 7 L, 10 L |
| Stainless Steel Vessels (benchtop scale): | 1 L to 30 L |
| Hybrid Glass/Steel Vessels (benchtop scale): | 1L to 30L |
| High Pressure Vessels (benchtop scale): | 500ml to 30L |
System Specifications
| Specification | Details |
|---|---|
| Working Volume | 50 mL to 20 L |
| Controller Options | Single or Twin |
| Agitation Types | Rushton, Marine, Pitched Blade, or custom impellers (0–2000 rpm) |
| Vessel Materials | Jacketed Glass, Stainless Steel, or Single-Use |
| Sensor Suite | pH, DO, temperature, ORP, foam, level, biomass (NIR), dissolved CO₂, conductivity |
| Temperature Control | +4°C to +90°C (±0.1°C) with optional chiller integration |
| Gas Control | MFCs or rotameters for Air, O₂, CO₂, N₂, CH₄, H₂ |
| Pumps | 4–6 variable-speed stepper peristaltic pumps |
| Scales | Integrated balances for vessel weight and feed rate monitoring |
| Automation & Software | Smart-BioFlex™ Software with real-time monitoring, remote access, data logging, and OPC-UA/Modbus integration |
| Online Analyzers | Cell viability, off-gas analysis (O₂, CO₂, CH₄, H₂, H₂S), glucose, and other configurable analytes |
Smart-BioFlex™ Software Suite
Smart-BioFlex™ is KBiotech’s intelligent Software—designed to offer the power of an industrial control system with the simplicity and clarity needed for fast-paced research and compliant bioprocessing.
Built for both beginners and seasoned bioprocess professionals, it enables intuitive control, real-time insights, and seamless integration—all in one elegant interface.
Key Features:
- Real-Time Monitoring & Predictive Control
Constant parameter tracking with real time adjustments for temperature, DO, pH, and more—ensuring stable, high-yield processes. - Advanced Batch Management
Easily create, duplicate, and modify batch runs with built-in recipe templates and guided parameter setup. - Smart Recipe Builder
Define multi-phase, condition-based recipes with steps linked to time, events, sensor values, or cascade control loops. - Flexible Cascade Controls
Configure custom cascades (e.g., DO to agitation, O₂ blending, or substrate feeding) across multiple control strategies. - Plug-and-Play Sensor Auto-Detection
Automatically recognizes and configures connected probes and sensors, simplifying initial setup and calibration. - Online Data Visualization
Live process trends, customizable charts, and intuitive graphical dashboards—track what matters in real time. - Data Logging & Audit Trail
21 CFR Part 11-compliant logging of all events, alarms, operator actions, and setpoints with secure time stamping. - Data Export & Analysis
Export in multiple formats (CSV, Excel, PDF), and integrate with LIMS or analysis tools via OPC-UA, Modbus, or REST API. - Remote Access & Multi-User Permissions
Web-based interface allows control and monitoring from any device. User roles and access levels help enforce security and traceability.
Optional Add-ons & Integrated Analyzers
- LIVE-CELL™: Inline viability detection via capacitance measurement
- KBIO-OD-CELL: Biomass sensor suite (optical + turbidity)
- KG-FERM™ Analyzer: Multi-gas real-time analyzer (O₂, CO₂, CH₄, H₂, H₂S)
- dCO₂ Sensors: Dissolved CO₂ monitoring integrated for precise culture control
- Gas Control Modules: MFC or rotameter-based systems
- Pump Modules: Single or multi-line peristaltic options
- Automated Sampling Ports: Sterile sampling with remote trigger capability
- Chillers: Dual-loop thermal regulation (Peltier or external loop)
All sensors and modules are seamlessly connected to the Smart-BioFlex™ control system, enabling fast setup, live data capture, and real-time analytics—ready out-of-the-box.
What Labs Are Saying
“Swiss precision from the first batch. Reproducibility and ease-of-use are unmatched.”
— EU Biotech Startup
“With the twin setup, we halved our optimization time. Fantastic system.”
— Pharma Dev Lead, US
“Compact, intuitive, and fully compliant. Exactly what we needed for CRISPR scale-up.”
— SynBio Lab, UK
