Automated, Compact Sterilization & Cleaning Unit for Vessels (1–5,000 L)
KB-BIO-SIP
Pilot & Industrial Stainless Steel SIP/CIP Bioreactors & Fermenters
At pilot and industrial scale, you don’t buy “a tank.”
You buy uptime, clean batches, and repeatable production.
KBiotech designs and delivers stainless steel SIP/CIP bioreactor and fermenter systems engineered around process
reality and manufacturing discipline—built to run in production, not to impress in a demo.
Most systems can run. We build systems you can run in production.
Choose the Right Benchtop System
Lab SIP Bioreactors
Scalable Stainless Steel Fermenters. Scale up with confidence.
Volume Range: 1L - 50L
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Pilot SIP Bioreactors
From development to production — scale with precision and compliance.
Volume Range: 20L - 500L
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Industrial SIP Bioreactors
Scale without limits — precision, reliability, and full GMP compliance.
Volume Range: 500L - 50.000L
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Accessories & options
Online Analyzer
Better control starts with better visibility.
BioBook systems can be equipped with process analytics (PAT) to improve comparability between runs and speed up optimization, especially in microbial fermentation (bacteria, yeasts, fungi) and cell culture.
- Off-gas analyzer: track respiration and process dynamics in real time.
- Biomass turbidity probe: monitor growth trends without waiting for offline samples.
- Dissolved CO₂ probe: improve control where CO₂ impacts
performance and viability Request a Quote Talk to an Engineer - Load cells: gravimetric feeding and mass balance for repeatable fed-batch operation.
What Makes KBiotech Different at Scale
Powerful software built for the full journey
Recipe execution, batch consistency, alarms, and data capture
designed to carry across the whole scale.
One unified SIP/CIP approach across the line
Cleaning and sterilization should not be patchwork. KB-BIO-SIP
systems align SIP/CIP cycles and routing so production remains
repeatable.
Flexible modules, upstream to downstream
KB-U modules integrate ancillary tanks for feeding/media/harvest and downstream interfaces such as centrifugation, filtration, and diafiltration (TFF).
Modular by design, so you can grow without rebuilding
Our systems are built as modular platforms so you can expand
capacity, add modules, or upgrade automation without redesigning the architecture.
Custom where it matters, standard where it must
We custom-engineer what drives performance (mixing, aeration,
feeding, transfers, cleaning paths) while keeping the system
structure maintainable and production-ready.
One control philosophy from pilot to industrial
Scale-up fails when the control layer changes. We keep control
logic and operator workflow consistent from pilot to industrial.
Get the right system
recommendation
Tell us your organism, application, and target volume. We’ll reply with a recommended system configuration.
Call us to contact our specialists
For presales questions mail us at
Frequently Asked Questions
KB-BIO-SIP-L covers 15–75 L, KB-BIO-SIP-P covers 100–500 L, KB-BIO-SIP-I covers 500–20,000 L. Configuration-dependent
Yes—KB-U modules can include CIP/SIP utilities, dosing/feeding, media/buffer tanks, harvest/hold, sterile transfer, and downstream interfaces (centrifugation, filtration, diafiltration/TFF).
Yes—KBiotech maintains a consistent control structure and operating workflow across scales.