Bioreacors & Fermenters Solutions

KBiotech produces compact and modular Bioreactors from laboratory scale to production in a range of vessel types, stirred-tanks or single-use, using advanced control technologies and process strategies to automate, intensify and improve your bioprocess. Fully scalable bioreactors from development to manufacturing starting from 50 mL w/v to 5 KL in standard or customized solutions. We also perform special and OEM projects for pilot and industrial plants up to 5KL and can handle the retrofitting and modernization of existing systems.

Kbiotech Bio-Book Compact Bioreactor

Compact Bioreactors & Fermenters

100ml to 20L

Glass, Single Use, Steel

Ease of use and small footprint

Bio-Book UP Modular Bioreactors

100ml to 50L

Glass, Single Use, Steel

Advanced modular and flexible system

Single Use Bioreactors and Fermentors

500ml to 30L

Single Use Polycarbonate, Gamma Irradiated

SUS & SUB disposable solutions

Twin Bioreactor

Twin Modular Bioreactors

100ml to 50L

Glass, Single Use, Steel

2 parallel vessels

Tween Bioreactors Single Use

Quad Modular Bioreactors

100ml to 50L

Glass, Single Use, Steel

4 parallel vessels

Parallel Modular Bioreactors

100ml to 30L

Glass, Single Use, Steel

Up to 12-24 parallel vessels

vessel sub 300-500ml

Mini Bioreactors 50ml – 1.000ml

Mini Bioreactors 50ml – 1.000ml Mini Bioreactor Fermentation Kbiotech introduce a new range of Mini Bioreactors for scale down and screening studies in fermentation and cell cultivation. Different configurations and set-up on a small volumes are available to reduce materials and consumables costs to improve development results at a lower scale. Mini Bioreactors are used to generate more data saving time and money. Our systems are engineered easy to use and upgradable at any time. Controller functionalities and architecture is the same from mini bioreactor to pilot scale to offer a better uniformity, simplicity and self confidence use to our…

vessel

Single Wall Vessels 300ml – 20L

Single Wall Vessels 300ml – 20L Vessels feature an autoclavable borosilicate glass body and stainless steel head plate. Stainless-steel dished or round bottom vessels are available with a strong heating blanket for rapid heat transfer ideal for microbial and yeasts fermentations. Interchangeable magnetic and direct overhead drive options, a variety of impellers and multiple industry standard head plate ports are available for user flexibility. Rushton, pitched-blade, marine blade, spinfilter, cell-lift and packed-bed impellers available Applications: Research and Development in cell culture and microbiology Laboratory and pilot scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi Cultivation of mammalian, insect, and…

vessel

Water Jacketed Vessels 300ml – 20L

Water Jacketed Vessels 300ml – 20L Perfect design for multi purpose applications Dished or round bottom vessels with stainless steel head plate designed according to the latest GMP requirements with a robust glass borosilicate vessel fully certified. Our double wall vessels are available with a precise electrical heating module for accurate and gentle heat transfer and temperature control for cell culture and microbial fermentations. Interchangeable magnetic and direct overhead drive options, a variety of impellers and multiple industry standard head plate ports are available for user flexibility. Rushton, pitched-blade, marine blade, spinfilter, cell-lift and packed-bed impellers available. Applications: Research and…

SINGLE-USE-VESSEL

SUB & SUS Vessels 300ml – 30L

SUB & SUS Vessels 300ml – 30L Kbiotech SUB disposable bioreactors solutions help you to save downtime and eliminate the need to clean, autoclave and assemble your classic glass bioreactors. You can benefit of our BIO BENCH COMPACT and ADVANCED Controllers platform to interchange and/or work in parallel your traditional STR glass bioreactors with the SUB disposable systems to boost your experiments. Our range of single-use, stirred tank bioreactor platform are available with sigle jacket and double wall vessels and enable you to get you to results faster. All of our SUB disposable vessels can be used for cell cultures…

Special & Customized Vessels

Special & Customized Vessels Air Lift / Gas Lift, Flat Panel & OEM Vessels KBiotech produce special vessels such as Air Lift / Gas Lift, Flat-panel and custom solutions for both laboratory and pilot applications. Air Lift vessels volume available: 3 L, 5-10-20-30 Liters or customized Flat-Panel volume available: 1 L, 3L-5-10-20-30 Liters or customized All vessels are compatible with our BIO-BOOK Compact and BIO-BOOK UP Modular control units, the configurations are adapted according to the specific needs of each customer. Applications Algae, Plant cell culture, Biofuels Biogas Biomolecules Wastewater remediation, Fungi fermentation, Bacterial cultures, Anaerobic fermentation, Cell culturing &…

PhotoBioreactors

PhotoBioreactors

For phototrophic organisms

laboratory Bioreactors

Laboratory Bioreactors In situ sterilizable 3L-50L

3L - 50L

Stainless Steel

Laboratory Bioreactors In situ sterilizable 3L-50L Laboratory SIP systems for fermentation & cell culture KBiotech Modular Laboratory in-situ Sterilizable Bioreactors & Fermenters from 3 Litres to 50 Litres volume The Modularity concept has been extended to our lab/pilot SIP in-situ sterilizable bioreactors and fermenters with leading industrial hardware and software technologies, in modular and compact designs, available as pre-assembled SIP bioreactor packages or custom-made solutions to suit our customers’ requirements. The major advantage of the modularity of Kbiotech bioreactors is the ability to integrate and replace any module at any time and to interchange a wide range of culture vessels…

Pilot Bioreactors

Pilot Bioreactors 50L-500L

15L to 500L

Stainless Steel

Pilot Bioreactors 50L-500L Kbiotech supplies a range of standardized & customized Pilot Bioreactors & Fermenters for your microbial culture needs – bacterial or yeast – as well as cell culture from 50 Liter to 500 Liters volume. Industrial design, Flexible automation, software and vessel solutions for pharmaceutical, biotechnological and food industries. All our systems can be fully documented for GLP and cGMP usage and are supplied with an extensive package of documentation to support validation and quality by design. Applications of our Pilot Bioreactors Biopharmaceuticals Pilot Production Clinical manufacturing Biopharmaceuticals Biosimilars Monoclonal Antibodies Vaccines mRNA Production Plasma and Blood derivates…

KG-FERM Gas Analyser

KG-FERM Gas Analyser Kbiotech offers a portable modular gas analyzer for laboratory installations, stainless steel pilot plants and also on industrial skids. The gas analyzer can be used for the analysis of exhaust gases from bioreactors, fermenters, storage and process tanks, flasks and laboratory shakers. The KG-FERM version is available with single or double channel for parallel Gas analysis. The gas analyzer has 4-20mA or Modbus analog output to be interfaced with KBiotech controllers and software, but also with those of other brands. The gases available are the following: O2, CO2, CH4, CO Kbiotech Bioflex Software also allows online data…

On-line Biomass Sensors

On-line Biomass Sensors Kbiotech solutions for Risk-based stoichiometric process management, quantitative and qualitative multi-parameter process analysis, boosting process knowledge and safety. Our solutions also include TURBIDOSTAT operational mode and feedback control loop. We offer the integration of online Biomass sensors such as Turbidity and Viable cell sensors compatible with the whole range of Kbiotech bioreactors, controllers and Bioflex sotware. Kbiotech Bioflex Software provide an online data recording option and data processing and feedback controlled actions based on the biomass measurements to improve your bioprocess, cell growth and productivity. On-line measurement of total cell density The KBIO-OD-CELL sensor performs on-line measurement…

Industrial Bioreactors SIP/CIP systems 500L-30.000L

500L to 30.000L

Stainless Steel

Industrial Bioreactors SIP/CIP systems 500L-30.000L Kbiotech design, engineer and manufacture quality Industrial process equipment, tailored to the specific needs, applications and budgets of our customers. Industrial Bioreactors and Fermenters volumes available from 500 Liters up to 30 KL (cubic metres), Others available on request. Our portfolio contains a powerful range of engineering and manufacturing solutions, integrated to address the process and equipment needs which are critical to the cell-growth process. Our custom solutions meet industry best practice and local regulatory requirements. In addition, we provide extensive aftermarket service and support, including spare parts, equipment upgrades, servicing and maintenance, as well…

Tanks & Reactors

Tanks & Reactors for liquids, semi-solid and solids compounds Formulation, storage and filling Tanks Tanks Volume from 3 to 5000 liters as well as custom fit solutions. All Tanks can be supplied as stand-alone equipment (stationery or mobile) or as automated process units delivered as fully-functional modules installed on-site which include: agitators, homogenizers, metering and regulating technology, control units, valves and pipe connections. Options for hazardous environments are also available. Features Tanks made of stainless steel AISI 304, 316, 904 and high-alloy, special realizations are also possible Customized manufacturing Design: Single, double and triple wall design, heatable, insulated High quality…

Automation and Controllers

Automation & Controllers KBiotech has developed modern and advanced BioControllers with industrial automation technologies for the whole range of Bioreactors, Fermenters and process equipment in our portfolio from laboratory to pilot and production systems. We offer Compact and Modular control systems for various laboratory and industrial process needs. The systems designed by us allow rapid scale up or scale down thanks to the uniformity and intuitivity of the control logics of our automation and software systems. KBiotech FPGA industrial PLC technology guarantee the best performances, reliability, long-term service and spare parts availability, except for proprietary systems. The selection of trusted…

software bioflex

Bioflex Software

Bioflex Software Kbiotech Bioflex Software is a supervisory and data acquisition software to control laboratory, pilot and industrial bioreactors & fermenters remotely. Bioflex is a harmonized platform capable of running lab, pilot or industrial scale systems from simple batch to advanced and sophisticated fed-batch and continuous processes. Bioflex offers innovative features and can manage and control up to 12-24 bioreactors online. Bioflex is available in the standard version for R&D and process development and as SCADA Software system for manufacturing purpose with an advanced database for data analysis and data processing. Bioflex software is CFR21 part 11 compliant and OPC…

SIP/CIP Pilot

CIP/SIP Pilot In situ cleaning and sterilising system for Autoclavable and SIP Bioreactors Kbiotech supplies a range of standardized & customized Pilot Bioreactors & Fermenters for your microbial culture needs – bacterial or yeast – as well as cell culture from 20 Liter to 500 Liters volume. Industrial design, Flexible automation, software and vessel solutions for pharmaceutical, biotechnological and food industries. All our systems can be fully documented for GLP and cGMP usage and are supplied with an extensive package of documentation to support validation and quality by design. Applications General applications: Pilot Production Clinical manufacturing Biopharmaceuticals Biosimilars Monoclonal Antibodies…

Intelligent Modules for new bioreactors or for upgrades of existing machines

Intelligent Modules for new bioreactors or for upgrades of existing machines

benchtop brioeactors

BioBook Compact

50 ml - 20 L

Glass, Single Use, Stainless Steel

Next-generation scalability and control, in one compact platform.

BioBook Modular Bioreactor

50 ml - 20 L

Glass, Single Use, Stainless Steel

The first truly modular benchtop platform that grows with your process.

BioBook parallel bioreactors

BioBook Parallel

50 ml - 20 L

Glass, Single Use, Stainless Steel

High-Throughput Benchtop Bioreactor System that supports up to 12 independently controlled bioreactors.

Lab SIP Bioreactors

Lab SIP Bioreactors

1L - 50L

Steel, Stainless Steel

Scalable Stainless Steel Fermenters. Scale up with confidence.

Pilot SIP Bioreactors

Pilot SIP Bioreactors

20L - 500L

Stainless Steel

From development to production — scale with precision and compliance.

Industrial SIP Bioreactors

500L - 50.000L

Steel, Stainless Steel

Scale without limits — precision, reliability, and full GMP compliance.

Biogas reactor

Biogas, Bioplastics & CO₂ Fermentation Reactors (1L–20,000L)

1L - 20.000L

Steel, Stainless Steel

Why Choose Biogas, Bioplastics & CO₂ Fermentation Reactors? Modular scalability1L to 20,000L with unified control architecture Real-timeGas analytics (CH₄, CO₂, H₂, O₂) Real-timeGas analytics (CH₄, CO₂, H₂, O₂) Integrateswith upstream and downstream processes BIOFLEX™ SCADA platform21 CFR Part 11, GMP-ready Specialized impellersfor high-viscosity biopolymer fermentation Explosion-proof (ATEX/IECEx)for hazardous gas/dust zones Anti-corrosion and anti-biofilmvessel coatings available Technical Specifications Volumes Range 1L – 20,000L (custom scalable)Material 316L SS, Hastelloy, Borosilicate glassTemp Range 4°C – 150°C, dual-zonePressure Rating Up to 15 bargZones ATEX Gas 0–2, Dust 20–22Download Data SheetMixing OptionsMagnetic/top drive; Rushton, marine, helical Sensors pH, DO, ORP, foam, turbidity, biomass, gas-phaseCertifications CE,…

single use bioreactors

Single Use Bioreactors

500mL – 10L

Single Use

Bring fast, sterile, plug-and-run bioprocessing to cell culture, microbial fermentation, vaccines, and cell & gene therapy.

CIP & SIP Skids

1L - 5.000L

Stainless Steel

media preparation & buffer tanks

Media Preparation & Buffer Tanks (3L – 20.000L)

3L - 20.000L

Steel, Stainless Steel

Sterile, GMP-Compliant Stainless Steel Systems for Pharma, Biotech & Industrial Applications